2 punctuation - title made me wonder what kind of water "say water" was, or if this was a typo for "salt water"
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What do you call the act of drinking a whole bottle of, say, water in one go?

What do you call the act of drinking a whole bottle of, say, water in one go? It doesn't have to be water.

What do you call the act of drinking a whole bottle of say water in one go?

What do you call the act of drinking a whole bottle of say water in one go? It doesn't have to be water.

What do you call the act of drinking a whole bottle of, say, water in one go?

What do you call the act of drinking a whole bottle of, say, water in one go? It doesn't have to be water.

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What do you call the act of drinking a whole bottle of say water in one go?

What do you call the act of drinking a whole bottle of say water in one go? It doesn't have to be water.