Here is the parse:

He felt ||that the close first person perspective ||leaves the reader "too uncritically accepting of her worldview" ||and|| often leads reading and conversation about the novel towards supporting Jane.

there are two complements: leave the reader [etc.] + often leads to [etc].

They have equal weight structurally. Therefore, there should be no comma. There is a parallel structure.

As in: This leaves the reader wonder ||and|| often leads to confusion.

Same idea.

Here is the parse:

He felt ||that the close first-person perspective ||leaves the reader "too uncritically accepting of her worldview" ||and|| often leads the reading and conversation about the novel in a direction that supports Jane.

there are two complements: leave the reader [etc.] + often leads to [etc].

They have equal weight structurally. Therefore, there should be no comma. There is a parallel structure.

As in: This leaves the reader wonder ||and|| often leads to confusion.

Same idea.