The two phrases can mean the same thing.

Since the two persons are introducing themselves, 2 is inquiring about the person's major (AmE), or, as Wikipedia puts it:

the academic discipline to which an undergraduate student formally commits.

This is in contrast to, say, two friends who are inquiring about the current/up coming term. In such a case, 2 inquires about the particular subjects one might be studying that term, such as biology, math, and economics.

Question 1 usually inquires about one's committed disciple. So, Kabir could also have asked 1 in this case, and it would have meant the same thing as 1. Hence, Jackie responds "B.E.". We can infer that B.E. is Jackie's committed discipline, in either case.

The two phrases can mean the same thing.

Since the two persons are introducing themselves, 2 is inquiring about the person's major (AmE), or, as Wikipedia puts it:

the academic discipline to which an undergraduate student formally commits.

This is in contrast to, say, two friends who are inquiring about the current/up coming term. In such a case, 2 inquires about the particular subjects one might be studying that term, such as biology, math, and economics. This is because, presumably, the friends already know each other's committed disciplines.

Question 1 usually inquires about one's committed disciple. So, Kabir could also have asked 1 in this case, and it would have meant the same thing as 2. Hence, Jackie responds "B.E.". We can infer that B.E. is Jackie's committed discipline, in either case.