This question is asking you to choose two synonyms from a list to fill in the blank: (source)
Despite the general ______ of Roman archaeological studies toward the major cities and their monuments, archaeology has contributed much to a better understanding of rural developments in Roman territory.
A. openness
B. indifference
C. hostility
D. animus
E. bias
F. orientation
An unofficial answer is E/F, but after referring to the dictionary, I can't see why "orientation" is a synonym of "bias".
Meanwhile, I think C/D is also reasonable (contrary to their good understanding of rural developments).