The general principle is obviously that learners should be extremely cautious about "inventing" new terms, because they're so much more likely to get things wrong than native speakers.
Here's the full (subscription-only) Oxford English Dictionary definition for the relevant suffix...
-worthy (combining form)
Forming adjectives with the sense ‘deserving of what is specified by the first element’, as blameworthy adj., noteworthy adj., praiseworthy adj., etc.
Although I can easily guess1 what OP intends his neologism to mean, it should be fairly obvious that it doesn't really fit the pattern of the three examples above, which mean should be blamed / noted / praised.
The existing English word for the corresponding should be questioned sense is questionable, but that's obviously not the meaning OP intends.
It certainly doesn't help that blameable , notable, praisable are all "more or less" acceptable synonyms for the OED's examples, but things fall apart when we try to apply the pattern to question (questionworthy can't mean questionable).
In any case, apart from "That's a questionworthy question!", I can't really see where OP's neologism might be useful. And as all politicians know, the idiomatic standard there is "That's a good question!"
1 Thanks to @Lambie's comment, I now realise there are at least two possible meanings for OP's neologism questionworthy (describing an actual question which is worth asking, or someone's presentation which merits the audience asking questions afterwards).
Which just goes to show what can go wrong when you make up words, even if you think the meaning is obvious!