Usually genitives in -'s and preposition phrases headed by of mean pretty much the same thing; but when these modify nouns which are derived from active verbs or have an active sense there is usually a distinction:
For instance, in analyzing Thomas Mann's Dr. Faustus we might write about
the novel's study of artistic genius
Here we mean that the novelsubject studies artistic geniusobject.
Consequently, your D and E imply incorrectly that the study is performed by the novel, while A and C imply correctly that the study is performed upon the novel, just as other study is performed upon film.
It's not a hard-and-fast rule. A verb-derived noun which in context may be understood to express a passive meaning, in which the Subject is the Patient acted upon, may take a genitive expressing the Subject/Patient.
We're celebrating John'ssubject/agent completion of his novelobject/patient = John has completed the novel
We're celebrating the novel'ssubject/patient completion = The novel has been been completed