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I think most of these sentences are correct:

  1. A little bit of bread.
  2. A little of bread. (Is this correct?)
  3. A little of that.
  4. A little time gone.

  5. Some of that bread.

  6. Some people.

  7. Lots of work.

  8. A lot of work.
  9. Lots more.

If so, when do I use of after those words? (little, some, lots)

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  • No. 2 does not need "of". I can't really explain why though.
    – Dog Lover
    Nov 21 '16 at 21:30
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The explanation I found here seems alright.

We use of with (a) little and (a) few when they come before articles (a/an, the), demonstratives (this, that), possessives (my, your) or pronouns (him, them):

Put the flour into a bowl, blend with a little of the milk, beat in the egg yolks, then the sugar and the rest of the milk.

A few of his films were seen abroad.

All the sentences except 2 are correct.

A little bit of bread is fine because here, little describes bit of bread. Of has nothing to do with little. You say, a bit of something and a little bit of something.

A little of bread sounds unnatural. You could say a little bread or a little bit of bread instead.

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