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what can I write other words in place of "safer approach" that will appear nice to read as title. Context: xyz a "safer approach for the therapy".

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Usually

a safer approach

to doing something might be described as

a conservative approach
a traditional approach
a well-known approach
a time-honored approach

all four have the implied meaning that the "approach" being used has been tested and used over a longer period of time. In contrast to

a radical approach
a new approach
an innovative approach

Neither set of descriptions implies whether an approach is "correct" or will work only whether is might have been observed to work.

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