The joke is that this is a parody of another popluar meme.
From knowyourmeme.com, What in Tarnation,
"When you find a city slicker on FarmersOnly.com / wot n ternation"
“What in Tarnation?” is a rhetorical question meaning “what in damnation?”, which is often associated with Americans living in the Southern United States expressing incredulous bewilderment.
The meme above spawned many parody memes. Here are some of the memes.
Notice that the parodies have the hat in common, follow the formula what in X where X rhymes with tarnation, and the image is somehow related to X.
In the OP, notice that the image is of a bee, bees pollinate, and the act of pollinating is pollination.