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Does it mean "inspire someone"?
It would be the same thing. It would be, Find a passion, you know - Joseph Campbell said follow your bliss. Find something that absolutely gets you in the gut. Everything else comes if you’re really passionate about it. You’ll work the hours, do what it takes because you love what you’re doing. And you’ll probably live a lot longer.
In informal speech, gut is usually used to indicate an emotional, rather than an intellectual, response to something, for example:
gut feeling: intuition
gut reaction: initial feeling
gut-wrenching: deeply disturbing
The text that you quoted is not a standard idiom: the speaker probably meant something that you can be emotionally involved with. Earlier he uses the word passion, which fits with this interpretation.
