You should apply the cream which was prescribed by the doctor who has a better reputation to your skin.
Question: I am wondering if it's okay to have multiple adjective clauses in one sentence, and does adjective clause have any effect on the structure of the sentence(in terms of grammar).
Also, if the sentence will be grammatically correct if I change it into:
You should apply the cream which was prescribed by the doctor of/with better reputation to your skin.
In this case, I am wondering if the prepositional phrase is used correctly, and which preposition (with or of) works better in the context.