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Whenever we get so upset that we say or do something we later regret (and who doesn’t now and then?), that’s a sure sign that our amygdala—the brain’s radar for danger and the trigger for the fi ght-or-fl ight response—has hijacked the brain’s executive centers in the prefrontal cortex.

I searched the online dictionaries and cann't find any explanation for the phrase above.

So, Could you please tell me what it means?

The full text is here:

http://www.authorstream.com/Presentation/Mukteshwar-1855784-emotional-intelligence-resilience/

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"and who doesn't [do that]... ?" refers to the action or actions just mentioned. "Now and then" means "sometimes", "occasionally" or "from "time to time". It is a "rhetorical question", which is a question, asked in order to make a statement, that does not expect an answer. In this case the statement is "most people [do that] sometimes".

Who doesn't get so upset that they say or does something they later regret (Most people do that sometimes)?.

Rhetorical question
Now and then

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