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It is from this video. It is at 6 minute and 40 second. Here is the context:

But for those who have been, maybe, keyed upon this stuff or heard us discuss it before, or kind of tracking this concept of pain as output of the brain instead of input to the brain.

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Two possibilities:

  1. He said

But for those who have been, maybe, keyed up on this stuff or heard us discuss it before...

"be keyed up" means

Be nervous, tense, or excited, especially before an important event.

  1. He wanted to say

But for those who have keyed upon this stuff or heard us discuss it before...

where "key (in) on/upon" means

to focus one's attention, effort, etc. on

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