3

Does "how come" replace "how can you" in these phrases:

"How come you find the love of your life and walk away?"

"How come you win the lottery and gamble all the money away?"

4

Sort of. Usually, 'how come' is considered to be a synonym for 'why', but 'why' does not fit very well with the rest of the sentence without quite a bit of writing, so 'how can you' is a reasonable alternative. Or you could say something like:

Why is it that you find the love of your life and walk away?

'How come' and 'how comes' have a long heritage (Edmund Spenser, 1611), but are considered informal and colloquial. It is probably a shortened version of something like "how did it come about that".

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