The word sharp is just beyond its usual meaning and we all know that. In fact, when it comes to the human organs, sharp certainly means that they are more efficient in performing their duties!
Don't hide there. She'll catch you in a jiffy. She has very sharp eyes
StoneyB (Sir, I admire you!) has very sharp brain. He answers any question about the language English just like that.
But...
I'm afraid, no matter how hard we try to remove the smoke of cigarette from this room, my girlfriend will catch us. She has very sharp nose.
"Ah, never mind. I love people with sharp nose. They are sexy! BANG!!!
Sharp nose certainly means having a keen sense of smell but it, unlike eyes and brain, is also referred to the shape, the body part's sharpness - a pointed nose here?