We expect you to do great things with your work here. When that happens is up to you (with input from your manager, of course).
What does "with input from your manager, of course" mean? Does it mean that "of course you have to follow the direction from you manager"?
What's confusing for me is what this "with" exactly means. Does mean that "there will be input from your manager" or does it mean that "you should use/follow your manager's input"?