@Chenmunka's close, but actually, I think you mean:
Don't overlook the esteem of the person who values you the most.
Both @Chenmunka's sentence (with "worth of the person") and @helix's correction ("the value of the person") refer to the esteem in which "you" hold them, not the esteem in which they hold you.
That is, if you mean "Consider the source. If you think highly of someone, then don't discount it if they think highly of you." then, yes:
Don't overlook the worth of the person who values you the most
is close to what you want (but "overlook" is problematic).
If, however, you mean, "Don't discount the good opinion of someone holds of you just because they hold such a high opinion of you", then
Don't overlook the esteem of the person who values you the most.
is what you want.