The first sentence is impossible. "Beats" is conjugated to the present simple tense, which means it must have a subject and be the head of a clause. "Usyk" is the apparent subject, but it's also the object of "give". It cannot be both at once.
The second sentence is arguably ungrammatical, and while you might hear people say it in casual conversation, it's not idiomatic.
The correct structure here is: [ "give" + object + "a chance to" + base-form-verb ]
So the correct phrasing is, "What chance do you give Usyk to beat Joshua a second time?"