This is my second question marked to be closed. If I knew the language very well, I wouldn't ask any questions here. I removed the original question. Let the moderators write the question here the way they want!
The grammar of your sentences 1 and 2 are correct and natural and have the same function. They're interchangeable.
The meaning of the sentences is a bit odd because if the patient already knows the information, you cannot inform them, and if they don't know it, you can't confirm with them.
But I understand your question clearly enough and hope I've answered it.