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could anyone help me to get the difference between numb, dope, anesthetize and drug when we use them as verbs?

explanation with example would be appreciated.

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The words are all sort of related, though some are more slang-y and others are technical. I'm going to assume you mean the definitions that relate to each other and not the broader meanings. So, here they are, in order from most technical to least (in my opinion).

Anesthetize

This is the technical term for the act of numbing a patient before a medical procedure:

Merriam-Webster:

medical : to give drugs to (a patient) so that no pain can be felt : to give an anesthetic to (a patient)

The doctor anesthetized the patient [with] an intravenous injection.

Numb

As a verb, this means the same thing as anesthetize but it's a non-technical term, often used when talking directly to patients who may not know what the technical term means or by patients who don't want to use the technical term:

Wictionary

To cause to become numb.

The dentist gave me Novocaine to numb my tooth before drilling, thank goodness.

"I'm going to numb the area before we get started with the procedure."

It can also be more generally used, outside of the medical world:

Oxford Learners

to make a part of your body unable to feel anything, for example because of cold

His fingers were numbed with the cold.

Drug

This is used much more broadly than anesthetize because, while anesthetics are a type of drug, there are many others. This generally carries a negative connotation, though, so use with caution:

Oxford Learners:

to give a person or an animal a drug, especially to make them unconscious, or to affect their performance in a race or competition

He was drugged and bundled into the back of the car.

He was asleep, heavily drugged with tranquillizers.

It could also be used more informally/colloquially:

The doctor drugged me before the operation and I didn't feel a thing.

Dope

Dope is much more slang, though it's being used more and more in relation to sports drug use. The verb definition is almost identical to drug.

Oxford Learners:

to give a drug to a person or an animal in order to affect their performance in a race or sport

The wine was doped.

It can be used, very informally, in the medical sense:

I was so doped up on morphine, I don't remember anything that happened.

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    I'll disagree with anesthetize vs numb. To anesthetize means to administer an anesthetic. While a local anesthetic produces numbness, in line with your statement, a general anesthetic causes loss of consciousness. May 3, 2015 at 4:40
  • @WhatRoughBeast I agree that anesthetized and numb absolutely do not mean the same thing. en.wikipedia.org/wiki/Anesthesia Nov 6, 2015 at 20:58

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