Henry says, ‘The Emperor, two or three years back when he was in Germany, did he not have an evil humour in his thigh? They say the weather didn't suit him. But then his dominions offer a change of climate. Whereas from one part of my kingdom to the next there is no change to be found.’
— Wolf Hall by Hilary Mantel
Does "an evil humour" mean some kind of rheumatism or pain in his thigh?