I don't think it means either one; I think it means "she was gone from my life." In other words, I wouldn't be able to see her anymore (because the distance between us would be too great).
If my hunch is right, we could rewrite the sentence like this:
She hugged me tightly for a minute, and then I got on the plane, and I never saw her again.
Of course, it's hard to say for sure, because you haven't told us where you found this sentence. Quite often, the meaning of a sentence will change when the reader knows more about the surrounding context.
For example, if I gave you this sentence:
It took us two days to climb that mountain.
you probably imagine something like this:
But if I add a little more context:
It was really hard putting our son in rehab. He didn't want to go; he didn't think he had a problem. We spoke to him at length about why he should go, about how he was ruining is life. It wasn't easy, but we finally convinced him. It took us two days to climb that mountain.
Now it's apparent that the sentence has nothing to do with a physical mountain; that the phrase "climb a mountain" is being used as a metaphor, because the word mountain can be used metaphorically to mean problem.