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Best of Regina George https://www.youtube.com/watch?v=Y_dCc-9pEPM

Here are quotes from the movie "Mean Girls".

Regina: Wait. Sit down. Seriously, sit down. Why don't I know you?

Cady: I'm new. I just moved here from Africa.

Regina: What?

Cady: I used to be home-schooled.

Regina: Wait. What?

Cady: My mom taught me at home...

Regina: No, no. I know what home-school is. I'm not retarded. So you've actually never been to a real school before? Shut up. Shut up.

Cady: I didn't say anything.

What does Regina mean by "Shut up"? Thanks in advance.

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There, it is an exclamation of surprise and disbelief, like "Go on!" or "You don't say!" of yesteryear. If my sense of contemporary American pop culture is accurate, there's a gender bias, and "Shut up!" as an exclamation (not as a command to stop talking) is more often used by women than by men.

It also means "keep your mouth shut, i.e. stop talking", and that's why Cady says "I didn't say anything."

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