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I was wondering if the following sentence is correct:

The average teenager’s brain differs from that of an adult.

Can the place holder "from that of" be used in the sentence above?

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    Why do you doubt it? Nov 17, 2020 at 18:35

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In a word, yes.

In my opinion, I consider the usage slightly formal, so I would say "from an adult's", where "adult's" is a possessive pronoun. It works the same, and means the same.

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