It has been two hours since I have left LA.
It has been two hours since I left LA.
Both are correct. We can use the simple past or the present perfect after since depending on the meaning.
I left LA- simple past tense
I have left LA- present perfect tense
The simple past talks about the past. It does not tell us about the present.
The present perfect talks about the past and the present.
I left LA. (It refers to a point in the past, a time which is finished)
I have left LA. (It refers to a time leading up to the present, a time that continues from the past until now)